Monobenzonum [INN-Latin]
Brand names,
Monobenzonum [INN-Latin]
Analogs
Monobenzonum [INN-Latin]
Brand Names Mixture
Monobenzonum [INN-Latin]
Chemical_Formula
C21H22N2O5S
Monobenzonum [INN-Latin]
RX_link
http://www.rxlist.com/cgi/generic3/nafcillin.htm
Monobenzonum [INN-Latin]
fda sheet
Monobenzonum [INN-Latin]
msds (material safety sheet)
Monobenzonum [INN-Latin]
Synthesis Reference
No information avaliable
Monobenzonum [INN-Latin]
Molecular Weight
414.476 g/mol
Monobenzonum [INN-Latin]
Melting Point
No information avaliable
Monobenzonum [INN-Latin]
H2O Solubility
Soluble
Monobenzonum [INN-Latin]
State
Solid
Monobenzonum [INN-Latin]
LogP
3.373
Monobenzonum [INN-Latin]
Dosage Forms
Powder for solution
Monobenzonum [INN-Latin]
Indication
For the treatment of infections caused by penicillinase-producing staphylococci which have demonstrated susceptibility to the drugs.
Monobenzonum [INN-Latin]
Pharmacology
Nafcillin is a semisynthetic antibiotic substance derived from 6-amino-penicillanic acid. The drugs in this class are highly resistant to inactivation by staphylococcal penicillinase and are active against penicillinase-producing and non penicillinase-producing strains of Staphylococcus aureus. The penicillinase- resistant penicillins are active in vitro against a variety of other bacteria.
Monobenzonum [INN-Latin]
Absorption
No information avaliable
Monobenzonum [INN-Latin]
side effects and Toxicity
Serious toxicity is unlikely following large doses of nafcillin. Acute ingestion of large doses of nafcillin may cause nausea, vomiting, diarrhea and abdominal pain. Acute oliguric renal failure and hematuria may occur following large doses.
Monobenzonum [INN-Latin]
Patient Information
Monobenzonum [INN-Latin]
Organisms Affected
Enteric bacteria and other eubacteria